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Devil’s Lettuce Strain Review | Effects, Flavor & Grow

Devil’s Lettuce Strain Review | Effects, Flavor & Grow

Jan 12th 2026

Devil’s Lettuce Strain Review: Spicy Herbal Flavor, Potent Effects & Grow Guide

The Devil’s Lettuce strain is a bold, high-potency hybrid known for its pungent aroma, spicy herbal flavor, and powerful effects that live up to its infamous nickname. With strong euphoric onset and a relaxing finish, Devil’s Lettuce is popular among experienced users who enjoy intense flavor and long-lasting highs. This guide covers its genetics, aroma, effects, THC levels, and cultivation traits.

Intro

Devil’s Lettuce is a potent hybrid that delivers a fast-acting cerebral buzz followed by steady body relaxation. Often associated with classic skunky and herbal profiles, this strain offers a throwback feel with modern potency. Best suited for afternoon or evening use, Devil’s Lettuce is favored for stress relief, mood elevation, and unwinding without immediate couch-lock.

Genetics & Background

Because “Devil’s Lettuce” is used as a nickname for cannabis, genetics can vary by grower. Most versions are bred from classic skunk and kush-influenced hybrids, often incorporating OG or diesel-leaning genetics.

Common genetic traits include:

  • Strong skunky and herbal aroma
  • Dense buds with heavy trichome coverage
  • Balanced hybrid effects
  • High THC potential

The result is a strain that emphasizes pungency, potency, and classic cannabis character.

Aroma, Flavour & Terpenes

Devil’s Lettuce delivers a sharp, pungent aroma dominated by skunk, spice, and earthy herbs. Some phenotypes show hints of diesel, pepper, or citrus peel beneath the funk.

Common dominant terpenes include:

  • Caryophyllene – peppery spice and stress relief
  • Myrcene – earthy depth and body relaxation
  • Limonene – light citrus brightness and mood uplift
  • Pinene – herbal freshness and mental clarity

The flavor is bold and old-school, offering spicy herb and skunk on the inhale with an earthy, slightly gassy finish.

Effects & Uses

Devil’s Lettuce delivers strong, noticeable effects that begin with mental stimulation before easing into full-body calm.

Common effects include:

  • Euphoric head high
  • Elevated mood and laughter
  • Relaxed but present body feel
  • Calm focus and mental clarity
  • Mild sedation at higher doses

Popular medical uses:

  • Stress and anxiety relief
  • Depression and low mood
  • Mild to moderate pain
  • Appetite stimulation

Its balanced profile makes it versatile, though potency favors intermediate to experienced users.

Risks & Considerations

Due to its strength and pungency, Devil’s Lettuce may feel intense for beginners.

Possible side effects:

  • Dry mouth and dry eyes
  • Light dizziness
  • Anxiety if overconsumed
  • Drowsiness during comedown

Starting with a moderate dose helps maintain a comfortable experience.

Potency and THC Levels

Devil’s Lettuce typically tests between 20% and 28% THC, depending on phenotype and cultivation. CBD levels are generally low.

This potency supports:

  • Fast-acting euphoria
  • Long-lasting effects
  • Strong flavor expression

Well-suited for users seeking classic potency with modern strength.

Grow Info

Devil’s Lettuce is moderately easy to grow and tends to produce aromatic, resin-rich buds.

Indoor cultivation:

Flowering time: 8–9 weeks

  • Yield: 350–500 g/m²
  • Strong odor control recommended
  • Responds well to topping and LST

Outdoor cultivation:

  • Harvest: Late September to early October
  • Yield: 450–600 g per plant
  • Thrives in warm, dry climates

Proper curing enhances its skunky aroma and smooths the smoke.

Final Thoughts

Devil’s Lettuce is a classic-style, high-potency hybrid offering bold aroma, strong effects, and nostalgic cannabis character. With its skunky spice profile and balanced high, it appeals to users who appreciate old-school flavor with modern THC levels.

For those seeking a strain that delivers pungency, potency, and personality, Devil’s Lettuce lives up to its legendary name.